Excipient (pharmacologically inactive substance)
What is it?
Starches are typically derived from corn or potato. Starches are used in the pharmaceutical industry for a wide variety of reasons, such as an excipient, a tablet and capsule diluent, a tablet and capsule disintegrant, a glidant, or as binder. Disintegrants enable tablets and capsules to break down into smaller fragments (dissolve) so that the drug can be released for absorption. Starches also absorb water rapidly, allowing tablets to disintegrate appropriately.
Starches are also used in the food manufacturing industry for processing, and as food thickeners or stabilizers. There are many other diverse uses for starches in the manufacturing industry. Pregelatinized starch derives primarily from corn, has been cooked and then dried. Instant puddings, pie fillings, soup mixes, salad dressings, candy often contain pregelatinized starch.
Pregelatinized starches (dried, cooked starches) are highly digestible. Consumption of excessive quantities of raw starch has resulted in obesity and iron-deficiency anemia in human subjects. However, there is no evidence to suspect a hazard to the public when they are used at levels that are now current or that might reasonably be expected in the future.
 Dave RH. Overview of pharmaceutical excipients used in tablets and capsules. Drug Topics (online). Advanstar. 10/24/2008 http://drugtopics.modernmedicine.com/drugtopics/Top+News/Overview-of-pharmaceutical-excipients-used-in-tabl/ArticleStandard/Article/detail/561047. Accessed 08/19/2011
Top Medications with this excipient
- Atarax 10 mg
- Atarax 25 mg
- Atarax hydrochloride 50 mg
- Benazepril Hydrochloride 5 mg
- Cardene SR 30 mg
- Dantrium 100 mg
- Dantrium 50 mg
- Dantrium 25 mg
- Dexamethasone 1 mg
- Dexamethasone 1.5 mg
- Disopyramide Phosphate 150 mg
- Fluconazole 200 mg
- Fluconazole 150 mg
- Levetiracetam 500 mg
- Lioresal 10 MG
- Nolvadex 10 mg
- Renese 4 mg
- Ser-ap-ES 25 mg / 15 mg / 0.1 mg
- Tambocor 150 mg
- Theophylline Extended-Release 125 mg