Sodium Starch Glycolate
Medically reviewed by Drugs.com. Last updated on Jan 17, 2022.
Excipient (pharmacologically inactive substance)
What is it?
Sodium starch glycolate is the sodium salt of carboxymethyl ether. Starch glycolates are of rice, potato, wheat or corn origin. Sodium starch glycoate is a white to off-white, tasteless, odorless, relatively free flowing powder.
Sodium starch glycolate is used as a pharmaceutical grade dissolution excipient for tablets and capsules. Sodium starch glycolate absorbs water rapidly, resulting in swelling which leads to rapid disintegration of tablets and granules. It is used as a disintegrant, a suspending agent and as a gelling agent. Without a disintegrant, tablets may not dissolve appropriately and may effect the amount of active ingredient absorbed, thereby decreasing effectiveness.  
Top Medications with this Excipient
- Acetaminophen 650 mg
- Dexamethasone 4 mg
- Dexamethasone 6 mg
- Ethmozine 200 MG
- Ethmozine 250 MG
- Ethmozine 300 MG
- Loperamide Hydrochloride 2 mg
- Prednisone 1 mg
- Topiramate 50 mg
- Topiramate 25 mg
- Topiramate 100 mg
- Topiramate 200 mg
- Zolpidem Tartrate Extended-Release 6.25 mg
- Zolpidem Tartrate Extended-Release 12.5 mg
 Dave RH. Overview of pharmaceutical excipients used in tablets and capsules. Drug Topics (online). Advanstar. 10/24/2008 http://drugtopics.modernmedicine.com/drugtopics/Top+News/Overview-of-pharmaceutical-excipients-used-in-tabl/ArticleStandard/Article/detail/561047. Accessed 08/19/2011
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