Excipient (pharmacologically inactive substance)
What is it?
Sodium bicarbonate, NaHCO3, is a common ingredient in effervescent powders and tablets. It is used with an acidic agent, such as citric or tartaric acid, to cause a reaction that produces carbon dioxide (CO2). The carbon dioxide leads to the resultant fizzing of the effervescent powder, such as seen with Alka-Seltzer.
Effervescent tablets and powders are widely used to deliver medicines contained antacids, pain medications, and cough or cold medicines. They dissolve quickly, are stable, convenient and easy to carry.
All carbonate salts on the FDA generally regarded as safe list. There is no evidence in the available information on calcium carbonate, potassium carbonate, potassium bicarbonate, sodium carbonate, sodium bicarbonate, or sodium sesquicarbonate that demonstrates or suggests reasonable grounds to suspect a hazard to the public when used at levels that are now current or that might reasonably be expected in the future.
 FDA’s SCOGS database; carbonates; SCOGS-Report Number: 26; Accessed 8/17/2012. http://www.fda.gov/Food/FoodIngredientsPackaging/GenerallyRecognizedasSafeGRAS/GRASSubstancesSCOGSDatabase/ucm260329.htm
Top Medications with this excipient
- Alavert (Orally Disintegrating) 10 mg ()
- Atorvastatin Calcium 10 mg ()
- Atorvastatin Calcium 80 mg ()
- Binosto 70 mg ()
- Bupropion Hydrochloride Extended-Release (XL) 150 mg ()
- Bupropion Hydrochloride Extended-Release (XL) 300 mg ()
- Carbidopa and Levodopa 25 mg / 100 mg ()
- Carbidopa and Levodopa 25 mg / 250 mg ()
- Clozapine (Orally Disintegrating) 100 mg ()
- Divalproex Sodium Delayed Release 500 mg ()
- Divalproex Sodium Delayed-Release 125 mg ()
- Divalproex Sodium Delayed-Release 500 mg ()
- Enalapril Maleate 10 mg ()
- Enalapril Maleate 20 mg ()
- Enalapril Maleate and Hydrochlorothiazide 5 mg / 12.5 mg ()
- Fentora 400 mcg ()
- Hydroxychloroquine Sulfate 200 mg ()
- Pravastatin Sodium 20 mg ()
- Pravastatin Sodium 80 mg ()
- Zomig-ZMT 2.5 mg ()