Poloxamer 188
Medically reviewed by Drugs.com. Last updated on Apr 18, 2022.
Excipient (pharmacologically inactive substance)
What is it?
Poloxamers are polymers used for drug delivery as formulation excipients. They are used in pharmaceutical formulations as surfactants, emulsifying agents, solubilizing agent, dispersing agents, and as in vivo absorbance enhancers. They are also used in topical dosage forms and rectal suppositories. The common available grades are poloxamer 68, 88, 98, 108, 124, 188, 237, 338, and 407.[1]
Top medications with this excipient
- Atovaquone and Proguanil Hydrochloride 250 mg / 100 mg
- Atovaquone and Proguanil Hydrochloride 62.5 mg / 25 mg
- Esomeprazole Magnesium Delayed-Release 20 mg
- Hydrochlorothiazide and Irbesartan 12.5 mg / 300 mg
- Hydrochlorothiazide and Irbesartan 12.5 mg / 150 mg
- Hydrochlorothiazide and Irbesartan 12.5 mg / 150 mg
- Irbesartan 300 mg
- Lovastatin 10 mg
- Metoprolol Succinate Extended-Release 200 mg
- Metoprolol Succinate Extended-Release 25 mg
- Metoprolol Succinate Extended-Release 50 mg
- Metoprolol Succinate Extended-Release 100 mg
- Odomzo 200 mg
- PrandiMet 500 mg / 1 mg
- Rapamune 0.5 mg
- Repaglinide 0.5 mg
- Sirolimus 2 mg
- Sirolimus 1 mg
- Tasigna 200 mg
- Tasigna 50 mg
References
- Patel, HR, et al. Poloxamers: A pharmaceutical excipients with therapeutic behaviors. International Journal of PharmTech Research. Vol.1, No.2, pp 299-303 , April-June 2009. Accessed February 27, 2015 at http://www.sphinxsai.com/pdf/jpt_Ap_Ju_09/PT=35%20%20Rakesh%20Patel%20%28299-303%29.pdf
Further information
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