Poloxamer 188
Excipient (pharmacologically inactive substance)
What is it?
Poloxamers are polymers used for drug delivery as formulation excipients. They are used in pharmaceutical formulations as surfactants, emulsifying agents, solubilizing agent, dispersing agents, and as in vivo absorbance enhancers. They are also used in topical dosage forms and rectal suppositories. The common available grades are poloxamer 68, 88, 98, 108, 124, 188, 237, 338, and 407.[1]
[1] Patel, HR, et al. Poloxamers: A pharmaceutical excipients with therapeutic behaviors. International Journal of PharmTech Research. Vol.1, No.2, pp 299-303 , April-June 2009. Accessed February 27, 2015 at http://www.sphinxsai.com/pdf/jpt_Ap_Ju_09/PT=35%20%20Rakesh%20Patel%20%28299-303%29.pdf
Top Medications with this excipient
- Avapro 75 mg (Bristol-Myers Squibb)
- Avapro 150 mg (Bristol-Myers Squibb)
- Avapro 300 mg (Bristol-Myers Squibb)
- Benazepril Hydrochloride and Hydrochlorothiazide 5 mg / 6.25 mg (Sandoz Pharmaceuticals Inc.)
- Benazepril Hydrochloride and Hydrochlorothiazide 20 mg / 25 mg (Sandoz Pharmaceuticals Inc.)
- Benazepril Hydrochloride and Hydrochlorothiazide 20 mg / 12.5 mg (Sandoz Pharmaceuticals Inc.)
- Bosulif 500 mg (Pfizer Inc.)
- Fenoglide 40 mg (Sciele Pharma Inc.)
- Fenoglide 120 mg (Sciele Pharma Inc.)
- Hydrochlorothiazide and Irbesartan 12.5 mg / 150 mg (Lupin Pharmaceuticals, Inc.)
- Hydrochlorothiazide and Irbesartan 12.5 mg / 150 mg (Watson Laboratories, Inc.)
- Hydrochlorothiazide and Irbesartan 12.5 mg / 300 mg (Watson Laboratories, Inc.)
- Irbesartan 75 mg (Teva Pharmaceuticals USA Inc.)
- Irbesartan 150 mg (Teva Pharmaceuticals USA Inc.)
- Irbesartan 300 mg (Teva Pharmaceuticals USA Inc.)
- Mefloquine Hydrochloride 250 mg (Teva Pharmaceuticals USA)
- Metoprolol Succinate Extended-Release 50 mg (Watson Pharmaceuticals)
- Metoprolol Succinate Extended-Release 25 mg (Watson Pharmaceuticals)
- Metoprolol Succinate Extended-Release 200 mg (Watson Laboratories, Inc.)
- PrandiMet 500 mg / 2 mg (Novo Nordisk Pharmaceuticals Inc)
