Poloxamer 188
Excipient (pharmacologically inactive substance)
Medically reviewed by Drugs.com. Last updated on April 17, 2020.
What is it?
Poloxamers are polymers used for drug delivery as formulation excipients. They are used in pharmaceutical formulations as surfactants, emulsifying agents, solubilizing agent, dispersing agents, and as in vivo absorbance enhancers. They are also used in topical dosage forms and rectal suppositories. The common available grades are poloxamer 68, 88, 98, 108, 124, 188, 237, 338, and 407.[1]
Top Medications with this excipient
- Alprazolam Extended Release 0.5 mg
- Atovaquone and Proguanil Hydrochloride 250 mg / 100 mg
- Atovaquone and Proguanil Hydrochloride 62.5 mg / 25 mg
- Benazepril Hydrochloride and Hydrochlorothiazide 20 mg / 25 mg
- Duavee bazedoxifene 20 mg / conjugated estrogens 0.45 mg
- Envarsus XR 0.75 mg
- Fenofibrate 120 mg
- Griseofulvin (Ultramicrocrystalline) 125 mg
- Irbesartan 300 mg
- Irbesartan 150 mg
- Irbesartan 300 mg
- Lovastatin 40 mg
- Malarone pediatric 62.5 mg / 25 mg
- Metformin Hydrochloride and Repaglinide 500 mg / 1 mg
- Metoprolol Succinate Extended-Release 25 mg
- Metoprolol Succinate Extended-Release 50 mg
- Metoprolol Succinate Extended-Release 100 mg
- Repaglinide 2 mg
- Sirolimus 1 mg
- Valsartan 80 mg
References
[1] Patel, HR, et al. Poloxamers: A pharmaceutical excipients with therapeutic behaviors. International Journal of PharmTech Research. Vol.1, No.2, pp 299-303 , April-June 2009. Accessed February 27, 2015 at http://www.sphinxsai.com/pdf/jpt_Ap_Ju_09/PT=35%20%20Rakesh%20Patel%20%28299-303%29.pdf
Further information
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