Excipient (pharmacologically inactive substance)
Medically reviewed by Drugs.com. Last updated on Dec 18, 2018.
What is it?
Poloxamers are polymers used for drug delivery as formulation excipients. They are used in pharmaceutical formulations as surfactants, emulsifying agents, solubilizing agent, dispersing agents, and as in vivo absorbance enhancers. They are also used in topical dosage forms and rectal suppositories. The common available grades are poloxamer 68, 88, 98, 108, 124, 188, 237, 338, and 407.
 Patel, HR, et al. Poloxamers: A pharmaceutical excipients with therapeutic behaviors. International Journal of PharmTech Research. Vol.1, No.2, pp 299-303 , April-June 2009. Accessed February 27, 2015 at http://www.sphinxsai.com/pdf/jpt_Ap_Ju_09/PT=35%20%20Rakesh%20Patel%20%28299-303%29.pdf
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