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Hydroxypropyl Cellulose

Excipient (pharmacologically inactive substance)

What is it?

Hydroxypropyl cellulose, also commonly known as hydroxypropyl methycellulose (HPMC) or hypromellose is a coating agent and film-former used as an inactive ingredient in the pharmaceutical industry. It has also been used as a rate-controlling polymer for sustained-release dose forms.[1]

As a powder, hypromellose is off-white to beige and may be in granules. Hypromellose is considered an inert ingredient. It has a high viscosity and is often used in ophthalmic preparations as artificial tears for dry eyes. In the US, it is available over-the-counter (OTC) in such products as Isopto-Tears and Nature’s Tears.[2]

[1] Dave RH. Overview of pharmaceutical excipients used in tablets and capsules. Drug Topics (online). Advanstar. 10/24/2008 Accessed 2/10/2017

[2] Lacrisert Insert. Product Monograph. Accessed 2/10/2017 at

Top Medications with this excipient