Hydrogenated Castor Oil
Excipient (pharmacologically inactive substance)
What is it?
As a pharmaceutical grade inactive ingredient, castor oil is used to emulsify and solubilize oils and other water-insoluble substances. A brand name product that contains castor oil is Cremophor and it contains a range of non-ionic polyethoxylated detergents. It was originally developed for use as solubilizers and emulsifiers. This research grade product is intended for use in R&D and development only. Hydrogenated castor oil (castor wax) is also used an extended release agent; stiffening agent; tablet and capsule lubricant. Castor oil has been used as a stimulant laxative to relieve occasional constipation, but it is rarely used today due to gentler and safer alternatives.[1]
[1] [1]Dave RH. Overview of pharmaceutical excipients used in tablets and capsules. Drug Topics (online). Advanstar. 10/24/2008 http://drugtopics.modernmedicine.com/drugtopics/Top+News/Overview-of-pharmaceutical-excipients-used-in-tabl/ArticleStandard/Article/detail/561047. Accessed 03/27/2014
Top Medications with this excipient
- Amlodipine Besylate and Benazepril Hydrochloride 5 mg / 20 mg ()
- Amlodipine Besylate and Benazepril Hydrochloride 5 mg / 10 mg ()
- Amlodipine Besylate and Benazepril Hydrochloride 10 mg / 40 mg ()
- Amlodipine Besylate and Benazepril Hydrochloride 5 mg / 10 mg ()
- Cefuroxime Axetil 500 mg ()
- Cefuroxime Axetil 125 mg ()
- Clopidogrel Bisulfate 75 mg (base) ()
- Clopidogrel Bisulfate 75 mg (base) ()
- Coreg CR 80 mg ()
- Diclofenac Sodium and Misoprostol 50 mg / 200 mcg ()
- Diclofenac Sodium and Misoprostol 75 mg / 200 mcg ()
- Lotrel 5 mg / 20 mg ()
- Misoprostol 200 mcg ()
- Requip XL 4 mg ()
- Requip XL 6 mg ()
- Ropinirole Hydrochloride Extended-Release 2 mg ()
- Ropinirole Hydrochloride Extended-Release 2 mg ()
- Valacyclovir Hydrochloride 500 mg ()
- Zenpep pancrelipase (10,000 units lipase, 34,000 units protease, 55,000 units amylase) ()
- Zonisamide 100 mg ()
