Hydrogenated Castor Oil
Excipient (pharmacologically inactive substance)
What is it?
As a pharmaceutical grade inactive ingredient, castor oil is used to emulsify and solubilize oils and other water-insoluble substances. A brand name product that contains castor oil is Cremophor and it contains a range of non-ionic polyethoxylated detergents. It was originally developed for use as solubilizers and emulsifiers. This research grade product is intended for use in R&D and development only. Hydrogenated castor oil (castor wax) is also used an extended release agent; stiffening agent; tablet and capsule lubricant. Castor oil has been used as a stimulant laxative to relieve occasional constipation, but it is rarely used today due to gentler and safer alternatives.[1]
[1] [1]Dave RH. Overview of pharmaceutical excipients used in tablets and capsules. Drug Topics (online). Advanstar. 10/24/2008 http://drugtopics.modernmedicine.com/drugtopics/Top+News/Overview-of-pharmaceutical-excipients-used-in-tabl/ArticleStandard/Article/detail/561047. Accessed 03/27/2014
Top Medications with this excipient
- Amlodipine Besylate and Benazepril Hydrochloride 5 mg / 40 mg
- Arthrotec 75 mg / 200 mcg
- Benazepril Hydrochloride and Hydrochlorothiazide 20 mg / 12.5 mg
- Cefuroxime Axetil 125 mg
- Clopidogrel Bisulfate 300 mg (base)
- Clopidogrel Bisulfate 75 mg (base)
- Clopidogrel Bisulfate 75 mg (base)
- Coreg CR 80 mg
- Diclofenac Sodium and Misoprostol 50 mg / 200 mcg
- Levetiracetam Extended Release 500 mg
- Metformin Hydrochloride Extended-Release 750 mg
- Requip XL 6 mg
- Requip XL 4 mg
- Ropinirole Hydrochloride Extended-Release 8 mg
- Ropinirole Hydrochloride Extended-Release 4 mg
- Ropinirole Hydrochloride Extended-Release 6 mg
- Ultresa 46,000 USP units amylase; 23,000 USP units lipase; 46,000 USP units protease
- Ultresa 41,400 USP units amylase; 20,700 USP units lipase; 41,400 USP units protease
- Uroxatral 10 mg
- Zonisamide 25 mg
