Hydrogenated Castor Oil
Excipient (pharmacologically inactive substance)
What is it?
As a pharmaceutical grade inactive ingredient, castor oil is used to emulsify and solubilize oils and other water-insoluble substances. A brand name product that contains castor oil is Cremophor and it contains a range of non-ionic polyethoxylated detergents. It was originally developed for use as solubilizers and emulsifiers. This research grade product is intended for use in R&D and development only. Hydrogenated castor oil (castor wax) is also used an extended release agent; stiffening agent; tablet and capsule lubricant. Castor oil has been used as a stimulant laxative to relieve occasional constipation, but it is rarely used today due to gentler and safer alternatives.[1]
[1] [1]Dave RH. Overview of pharmaceutical excipients used in tablets and capsules. Drug Topics (online). Advanstar. 10/24/2008 http://drugtopics.modernmedicine.com/drugtopics/Top+News/Overview-of-pharmaceutical-excipients-used-in-tabl/ArticleStandard/Article/detail/561047. Accessed 03/27/2014
Top Medications with this excipient
- Amlodipine Besylate and Benazepril Hydrochloride 5 mg / 20 mg (Sandoz Inc.)
- Amlodipine Besylate and Benazepril Hydrochloride 10 mg / 20 mg (Dr. Reddy’s Laboratories Inc.)
- Amlodipine Besylate and Benazepril Hydrochloride 5 mg / 10 mg (Dr. Reddy’s Laboratories Inc.)
- Amlodipine Besylate and Benazepril Hydrochloride 5 mg / 20 mg (Dr. Reddy’s Laboratories Inc.)
- Amlodipine Besylate and Benazepril Hydrochloride 2.5 mg / 10 mg (Dr. Reddy’s Laboratories Inc.)
- Amlodipine Besylate and Benazepril Hydrochloride 2.5 mg / 10 mg (Sandoz Pharmaceuticals Inc.)
- Coreg CR 80 mg (GlaxoSmithKline)
- Coreg CR 10 mg (GlaxoSmithKline)
- Coreg CR 20 mg (GlaxoSmithKline)
- Dilacor XR 120 mg (Watson Pharmaceuticals)
- Dilacor XR 180 mg (Watson Pharmaceuticals)
- Dilacor XR 240 mg (Watson Pharmaceuticals)
- Lotrel 2.5 mg / 10 mg (Novartis Pharmaceuticals)
- Metformin Hydrochloride Extended-Release 750 mg (Torrent Pharmaceuticals)
- Ropinirole Hydrochloride Extended-Release 6 mg (Sandoz Inc.)
- Ultresa 41,400 USP units amylase; 20,700 USP units lipase; 41,400 USP units protease (Aptalis Pharma US, Inc.)
- Zenpep pancrelipase (5,000 units lipase, 17,000 units protease, 27,000 units amylase) (Eurand Pharmaceuticals Ltd.)
- Zenpep pancrelipase (3,000 units lipase, 10,000 units protease, 16,000 units amylase) (Eurand Pharmaceuticals Inc)
- Zonisamide 50 mg (Sandoz Pharmaceuticals Inc.)
- Zonisamide 25 mg (Sandoz Pharmaceuticals Inc.)
