Ethylcellulose (10 MPa.s)
Excipient (pharmacologically inactive substance)
What is it?
Ethylcellulose is a free-flowing, white to light tan powder used in the pharmaceutical and food manufacturing industries. It is prepared from wood pulp or cotton by treatment with alkali and ethylation of the alkali cellulose with ethyl chloride. Ethylcellulose is used in pharmaceutical industry as a coating agent, flavoring fixative, tablet binder and filler, and as a viscosity-increasing agent. Ethyl cellulose is also used in the food industry as an emulsifier.[1] [2]
There is very limited data detailing possible side effects of ethylcellulose; however it is included in the FDA generally regarded as safe (GRAS) Database of Substances (SCOGS) Reviews.[3]
[1] Dave RH. Overview of pharmaceutical excipients used in tablets and capsules. Drug Topics (online). Advanstar. 10/24/2008 http://drugtopics.modernmedicine.com/drugtopics/Top+News/Overview-of-pharmaceutical-excipients-used-in-tabl/ArticleStandard/Article/detail/561047. Accessed 08/19/2011
[2] Food and Agriculture Organization of the United States. Prepared at the 26th JECFA (1982), published in FNP 25 ( 1982) and FNP. 52 (1992). Accessed March 31, 2012. Ethylcellulose. http://www.fao.org/ag/agn/jecfa-additives/specs/Monograph1/Additive-178.pdf
[3] FDA’s SCOGS database; Ethylcellulose; SCOGS-Report Number: 25; http://www.accessdata.fda.gov/scripts/fcn/fcnDetailNavigation.cfm?rpt=scogsListing&id=365 Accessed March 31, http://www.accessdata.fda.gov/scripts/fcn/fcnDetailNavigation.cfm?rpt=scogsListing&id=119
Top Medications with this excipient
- Cartia XT 120 mg (Andrx Pharmaceuticals)
- Cartia XT 240 mg (Andrx Pharmaceuticals)
- Cartia XT 180 mg (Watson Laboratories, Inc.)
- Cartia XT 300 mg (Watson Pharmaceuticals)
- Galantamine Hydrobromide Extended Release 24 mg (Teva Pharmaceuticals USA)
- Galantamine Hydrobromide Extended Release 16 mg (Teva Pharmaceuticals USA)
- Galantamine Hydrobromide Extended Release 8 mg (Teva Pharmaceuticals USA)
- Metoprolol Succinate Extended-Release 50 mg (Dr. Reddy's Laboratories Limited)
- Metoprolol Succinate Extended-Release 100 mg (Dr. Reddy's Laboratories Limited)
- Metoprolol Succinate Extended-Release 25 mg (Dr. Reddy's Laboratories Limited)
- Potassium Chloride Extended-Release 10 mEq (750 mg) (Watson Laboratories, Inc.)
- Potassium Chloride Extended-Release 20 mEq (1500 mg) (Watson Laboratories, Inc.)
- Taztia XT 360 mg (Watson Pharmaceuticals)
- Taztia XT 240 mg (Watson Pharmaceuticals)
- Taztia XT 180 mg (Watson Pharmaceuticals)
- Taztia XT 120 mg (Watson Pharmaceuticals)
- Taztia XT 300 mg (Watson Pharmaceuticals)
- Trospium Chloride Extended-Release 60 mg (Watson Laboratories, Inc.)
- Ursodiol 250 mg (Teva Pharmaceuticals USA)
- Ursodiol 500 mg (Teva Pharmaceuticals USA)
