D&C Red No. 27
Medically reviewed by Drugs.com. Last updated on Apr 18, 2025.
Excipient (pharmacologically inactive substance)
What is it?
D&C Red No. 27 is a drug and cosmetic synthetic dye. The FDA lists it as a safe additive for drugs and cosmetics as per FDA standards. D&C Red No. 27 may be safely used for coloring drugs generally in amounts consistent with current good manufacturing practice and all batches must be certified. In cosmetics, it can be used externally and in general cosmetics, including lipsticks, but is not to be used in cosmetics close to the eye.[1] Its use in coloring pharmaceuticals and cosmetics may only be of quantities allowable by the FDA.[1][2]
Some examples of medications containing D&C Red No. 27
- Amitriptyline Hydrochloride 10 mg
- Amphetamine and Dextroamphetamine 5 mg
- Amphetamine and Dextroamphetamine 15 mg
- Amphetamine and Dextroamphetamine 30 mg
- Amphetamine and Dextroamphetamine 20 mg
- Benadryl Allergy Ultratab diphenhydramine 25 mg
- Bismuth Subsalicylate (Chewable) 262 mg
- Diphenhydramine Hydrochloride 25 mg
- Diphenhydramine Hydrochloride 25 mg
- Diphenhydramine Hydrochloride 25 mg
- Diphenhydramine Hydrochloride 25 mg
- Estradiol 1 mg
- Excedrin Tension Headache acetaminophen 500 mg / caffeine 65 mg
- Ibuprofen (Chewable) 100 mg
- Metoprolol Tartrate 50 mg
- Metoprolol Tartrate 50 mg
- Morphine Sulfate Extended-Release 30 mg
- Oxycodone Hydrochloride 10 mg
- Oxycodone Hydrochloride 10 mg
- Oxymorphone Hydrochloride 10 mg
References
- U.S. Food and Drug Administration (FDA). Cosmetics. Color Additives Permitted for Use. Accessed 8/20/2012. http://www.fda.gov/Cosmetics/GuidanceComplianceRegulatoryInformation/VoluntaryCosmeticsRegistrationProgramVCRP/OnlineRegistration/ucm109084.htm
- U.S. Food and Drug Administration. Color Additives and Cosmetics. Updated 4/29/2007. Accessed 8/20/2012. http://www.fda.gov/ForIndustry/ColorAdditives/ColorAdditivesinSpecificProducts/InCosmetics/ucm110032.htm
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.