D&C Red No. 21
Excipient (pharmacologically inactive substance)
Medically reviewed by Drugs.com. Last updated on February 22, 2021.
What is it?
D&C Red No. 21 is a drug and cosmetic synthetic dye. The FDA lists it as a safe additive for drugs and cosmetics as per FDA standards. D&C Red No. 21 may be safely used for coloring drugs generally in amounts consistent with current good manufacturing practice and all batches must be certified. In cosmetics, it can be used externally and in general cosmetics, including lipsticks, but is not to be used in cosmetics close to the eye. Its use in coloring pharmaceuticals and cosmetics may only be of quantities allowable by the FDA.
 U.S. Food and Drug Administration (FDA). Cosmetics. Color Additives Permitted for Use. Accessed 8/20/2012. http://www.fda.gov/Cosmetics/GuidanceComplianceRegulatoryInformation/VoluntaryCosmeticsRegistrationProgramVCRP/OnlineRegistration/ucm109084.htm
 U.S. Food and Drug Administration. Color Additives and Cosmetics. Updated 4/29/2007. Accessed 8/20/2012. http://www.fda.gov/ForIndustry/ColorAdditives/ColorAdditivesinSpecificProducts/InCosmetics/ucm110032.htm
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