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Cetylpyridinium Chloride

Medically reviewed by Last updated on Dec 28, 2022.

Excipient (pharmacologically inactive substance)

What is it?

Cetylpyridium chloride is a common pharmaceutical ingredient. Cetylpyridium chloride is a cationic quaternary ammonium compound that can be found in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays It acts as an antimicrobial preservative; antiseptic; cationic surfactant; disinfectant; solubilizing agent; and wetting agent. As an active ingredient in oral antiseptics it has been noted to have a broad antimicrobial spectrum with a rapid bactericidal effect on gram-positive pathogens and a fungicide effect on yeasts.[1]

List of medications using Cetylpyridinium Chloride


  1. [1]Pitten FA, et al. Efficacy of cetylpyridinium chloride used as oropharyngeal antiseptic. Arzneimittelforschung.2001;51(7):588-95.

Further information

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