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Calcium Phosphate Dihydrate Dibasic

Medically reviewed by Last updated on Feb 2, 2024.

Excipient (pharmacologically inactive substance)

What is it?

Various calcium phosphates are used as diluents in the pharmaceutical industry. Diluents are added to pharmaceutical tablets or capsules to make the product large enough for swallowing and handling, and more stable.[1]

Some calcium phosphate salts can be anhydrous, meaning the water has been removed from the salt form. Other calcium phosphates are termed dibasic, meaning they have two replaceable hydrogen atoms.

Calcium phosphate dihydrate dibasic is on the FDA Generally Regarded as Safe List (GRAS). There is no evidence in the available information on calcium phopshate that demonstrates or suggests reasonable grounds to suspect a hazard to the public when they are used at levels that are now current or that might reasonably be expected in the future.[2]

List of medications using Calcium Phosphate Dihydrate Dibasic


  1. [1]Dave RH. Overview of pharmaceutical excipients used in tablets and capsules. Drug Topics (online). Advanstar. 10/24/2008 Accessed 03/24/2012
  2. FDA’s SCOGS database; calcium phosphate dibasic; SCOGS-Report Number: 32; Accessed March 24, 2012

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.