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Aluminum Sulfate

Excipient (pharmacologically inactive substance)

What is it?

Aluminum sulfate (Al2O12S3) exists as white, lustrous crystals, granules, or powder. In nature, it exists as the mineral alunogenite. Aluminum sulfate has an action similar to that of alum but is more stringent. A saturated solution is employed as a mild caustic. Solutions containing 5 to 10% have been used as local applications to ulcers and to arrest foul discharges from mucous surfaces. Aluminium sulfate is also used in the preparation of aluminium acetate ear drops. Aluminum sulfate is not classifiable as a human carcinogen. Aluminum sulfate used for multiple purposes in food for human consumption is generally recognized as safe when used in accordance with good manufacturing practice. According to the FDA, based on currently available evidence, there are inadequate data to establish general recognition of the safety and effectiveness of aluminum sulfate in antiperspirant and topical antifungal drug products.

[1] NCBI. PubChem. Aluminum sulfate compound summary. Accessed January 10, 2014. http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=24850#x125

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