Avastin FDA Approval History
Last updated by Judith Stewart, BPharm on May 5, 2021.
FDA Approved: Yes (First approved February 26, 2004)
Brand name: Avastin
Generic name: bevacizumab
Dosage form: Injection
Company: Genentech, Inc.
Treatment for: Colorectal Cancer, Non-Small Cell Lung Cancer, Glioblastoma Multiforme, Renal Cell Carcinoma, Cervical Cancer, Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer, Hepatocellular Carcinoma
Avastin (bevacizumab) is a recombinant humanized monoclonal IgG1 antibody for the treatment of colorectal cancer, non-small cell lung cancer, glioblastoma, renal cell carcinoma, cervical cancer, ovarian cancer, fallopian tube cancer, peritoneal cancer, and hepatocellular carcinoma.
Development Timeline for Avastin
|Oct 13, 2021||Approval FDA Approves Merck’s Keytruda (pembrolizumab) Plus Chemotherapy, With or Without Bevacizumab, as Treatment for Patients With Persistent, Recurrent or Metastatic Cervical Cancer Whose Tumors Express PD-L1 (CPS ≥1)|
|May 29, 2020||Approval FDA Approves Genentech’s Tecentriq in Combination With Avastin for People With Hepatocellular Carcinoma|
|Dec 6, 2018||Approval FDA Approves Genentech’s Tecentriq in Combination With Avastin and Chemotherapy for the Initial Treatment of Metastatic Non-Squamous Non-Small Cell Lung Cancer|
|Jun 13, 2018||Approval FDA Approves Genentech’s Avastin (bevacizumab) Plus Chemotherapy as a Treatment for Women With Advanced Ovarian Cancer Following Initial Surgery|
|Dec 5, 2017||Approval FDA Grants Genentech’s Avastin Full Approval for Most Aggressive Form of Brain Cancer|
|Dec 6, 2016||Approval FDA Approves Avastin (bevacizumab) Plus Chemotherapy for a Specific Type of Advanced Ovarian Cancer|
|Nov 14, 2014||Approval FDA Approves Avastin (bevacizumab) Plus Chemotherapy for Platinum-Resistant Recurrent Ovarian Cancer |
|Aug 14, 2014||Approval FDA Approves Avastin for Metastatic Cervical Cancer|
|Nov 18, 2011||Approval FDA Revokes Breast Cancer Indication for Avastin (bevacizumab)|
|Aug 3, 2009||Approval FDA Approves Avastin for the Most Common Type of Kidney Cancer|
|May 6, 2009||Approval FDA Grants Accelerated Approval of Avastin for Brain Cancer (Glioblastoma) That Has Progressed Following Prior Therapy|
|Feb 25, 2008||Approval FDA Grants Accelerated Approval of Avastin in Combination With
Paclitaxel Chemotherapy for First-Line Treatment of Advanced
HER2-Negative Breast Cancer|
|Oct 11, 2006||Approval FDA Approves Avastin in Combination With Chemotherapy for First-Line Treatment of Most Common Type of Lung Cancer|
|Apr 12, 2006||Avastin Filed in US for Treatment of Most Common Form of Lung Cancer|
|Feb 26, 2004||Approval Avastin Approved for treatment for Metastatic Colorectal Cancer|
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