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Vitamin K (Phytonadione) Injection

Last Updated: November 19, 2015
Status: Current

Vitamin K (Phytonadione) Injection

Reason for the Shortage
    • Amphastar had vitamin K injection on shortage due to increased demand for the product.
    • Oral vitamin K is not affected by this shortage.
Available Products
    • Vitamin K injection, Amphastar, 2 mg/mL, 0.5 mL SAF-T-JET prefilled syringe, 10 count, NDC 76329-1240-01
    • Vitamin K injection, Pfizer, 10 mg/mL, 1 mL ampule, 25 count, NDC 00409-9158-01
    • Vitamin K injection, Pfizer, 2 mg/mL, 0.5 mL ampule, 25 count, NDC 00409-9157-01

Estimated Resupply Dates

    • Amphastar and Hospira have Vitamin K injection available.


    • Avoid off-label oral administration of injectable Vitamin K during the shortage.
    • Vitamin K from Amphastar contains polysorbate 80 and propylene glycol.
    • Vitamin K from Hospira contains benzyl alcohol. The product labeling states there is no evidence to suggest toxicity of benzyl alcohol if used as recommended.


Updated November 19, 2015 by Michelle Wheeler, PharmD, Drug Information Specialist. Created June 29, 2015 by Michelle Wheeler, PharmD, Drug Information Specialist. Copyright 2017, Drug Information Service, University of Utah, Salt Lake City, UT.