Promethazine Hydrochloride Injection Shortage

Last Updated: September 4, 2025
Status: Current

Unavailable, Current:

• Phenergen, Injection, 25 mg/1 mL (Hikma Pharmaceuticals USA, Inc.)
• Phenergen, Injection, 50 mg/1 mL (Hikma Pharmaceuticals USA, Inc.)
• Promethazine Hydrochloride, Injection, 25 mg/1 mL (Hikma Pharmaceuticals USA, Inc.)
• Promethazine Hydrochloride, Injection, 50 mg/1 mL (Hikma Pharmaceuticals USA, Inc.)
• Promethazine Hydrochloride, Injection, 50 mg/1 mL (XGen Pharmaceuticals DJB, Inc.)

Limited Availability, Current:

• Promethazine Hydrochloride, Injection, 25 mg/1 mL (XGen Pharmaceuticals DJB, Inc.)

Available, Current:

• Phenergen, Injection, 50 mg/1 mL (Hikma Pharmaceuticals USA, Inc.)
• Promethazine Hydrochloride, Injection, 25 mg/1 mL (Hikma Pharmaceuticals USA, Inc.)
• Promethazine Hydrochloride, Injection, 50 mg/1 mL (Hikma Pharmaceuticals USA, Inc.)

Phenergen, Injection, 25 mg/1 mL (Hikma Pharmaceuticals USA, Inc.)

NDC Code: 0641-6084-25
Availability: Unavailable
Status: Current
Date of update: July 23, 2025
Update type: Revised
Reason for shortage: Other
Related Information: This presentation is temporarily on backorder. Recovery is TBD at this time.
Therapeutic category: Analgesia/Addiction; Gastroenterology; Pediatric; Pulmonary/Allergy
Initial posting date: November 21, 2023
Contact info: 800-631-2174

Phenergen, Injection, 50 mg/1 mL (Hikma Pharmaceuticals USA, Inc.)

NDC Code: 0641-6085-25
Availability: Unavailable
Status: Current
Date of update: July 23, 2025
Update type: Revised
Reason for shortage: Other
Related Information: This presentation is temporarily on backorder. Recovery is TBD at this time.
Therapeutic category: Analgesia/Addiction; Gastroenterology; Pediatric; Pulmonary/Allergy
Initial posting date: November 21, 2023
Contact info: 800-631-2174

Promethazine Hydrochloride, Injection, 25 mg/1 mL (Hikma Pharmaceuticals USA, Inc.)

NDC Code: 0641-0928-25
Availability: Unavailable
Status: Current
Date of update: July 23, 2025
Update type: Revised
Reason for shortage: Other
Related Information: This presentation is temporarily on backorder. Recovery is TBD at this time.
Therapeutic category: Analgesia/Addiction; Gastroenterology; Pediatric; Pulmonary/Allergy
Initial posting date: November 21, 2023
Contact info: 800-631-2174

Promethazine Hydrochloride, Injection, 25 mg/1 mL (Hikma Pharmaceuticals USA, Inc.)

NDC Code: 0641-1495-35
Availability: Unavailable
Status: Current
Date of update: July 23, 2025
Update type: Revised
Reason for shortage: Demand increase for the drug
Related Information: Additional lots are scheduled to be manufactured. Product will be made available as it is released.
Therapeutic category: Analgesia/Addiction; Gastroenterology; Pediatric; Pulmonary/Allergy
Initial posting date: November 21, 2023
Contact info: 800-631-2174

Promethazine Hydrochloride, Injection, 50 mg/1 mL (XGen Pharmaceuticals DJB, Inc.)

NDC Code: 39822-5550-6
Availability: Unavailable
Status: Current
Date of update: September 4, 2025
Update type: Revised
Reason for shortage: Demand increase for the drug
Related Information: Next lots scheduled for release February 2026.
Therapeutic category: Analgesia/Addiction; Gastroenterology; Other; Pulmonary/Allergy
Initial posting date: November 21, 2023
Contact info: 866-390-4411

Promethazine Hydrochloride, Injection, 50 mg/1 mL (Hikma Pharmaceuticals USA, Inc.)

NDC Code: 0641-0929-25
Availability: Unavailable
Status: Current
Date of update: July 23, 2025
Update type: Revised
Reason for shortage: Other
Related Information: This presentation is temporarily on backorder. Recovery is TBD at this time.
Therapeutic category: Analgesia/Addiction; Gastroenterology; Pediatric; Pulmonary/Allergy
Initial posting date: November 21, 2023
Contact info: 800-631-2174

Promethazine Hydrochloride, Injection, 25 mg/1 mL (XGen Pharmaceuticals DJB, Inc.)

NDC Code: 39822-5525-3
Availability: Limited Availability
Status: Current
Date of update: September 4, 2025
Update type: Revised
Reason for shortage: Demand increase for the drug
Therapeutic category: Analgesia/Addiction; Gastroenterology; Other; Pulmonary/Allergy
Initial posting date: November 21, 2023
Contact info: 866-390-4411

Phenergen, Injection, 50 mg/1 mL (Hikma Pharmaceuticals USA, Inc.)

NDC Code: 0641-6083-25
Availability: Available
Status: Current
Date of update: July 23, 2025
Update type: Revised
Related Information: Additional lots will be scheduled for manufacturing to meet demand. Product will be made available as it is released.
Therapeutic category: Analgesia/Addiction; Gastroenterology; Pediatric; Pulmonary/Allergy
Initial posting date: November 21, 2023
Contact info: 800-631-2174

Promethazine Hydrochloride, Injection, 25 mg/1 mL (Hikma Pharmaceuticals USA, Inc.)

NDC Code: 0641-6082-25
Availability: Available
Status: Current
Date of update: July 23, 2025
Update type: Revised
Related Information: Currently available. Additional product will be made available as it is released.
Therapeutic category: Analgesia/Addiction; Gastroenterology; Pediatric; Pulmonary/Allergy
Initial posting date: November 21, 2023
Contact info: 800-631-2174

Promethazine Hydrochloride, Injection, 50 mg/1 mL (Hikma Pharmaceuticals USA, Inc.)

NDC Code: 0641-1496-35
Availability: Available
Status: Current
Date of update: July 23, 2025
Update type: Revised
Related Information: Additional lots are scheduled to be manufactured. Product will be made available as it is released.
Therapeutic category: Analgesia/Addiction; Gastroenterology; Pediatric; Pulmonary/Allergy
Initial posting date: November 21, 2023
Contact info: 800-631-2174

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer