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Drug interactions between Viekira Pak and Viekira XR

Results for the following 2 drugs:
Viekira Pak (dasabuvir/ombitasvir/paritaprevir/ritonavir)
Viekira XR (dasabuvir/ombitasvir/paritaprevir/ritonavir)

Interactions between your drugs

There were no interactions found in our database between Viekira Pak and Viekira XR. However, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

Viekira Pak

A total of 874 drugs (4643 brand and generic names) are known to interact with Viekira Pak.

Viekira XR

A total of 874 drugs (4643 brand and generic names) are known to interact with Viekira XR.

Drug and food interactions

Moderate

ritonavir food

Applies to: Viekira Pak (dasabuvir / ombitasvir / paritaprevir / ritonavir), Viekira XR (dasabuvir / ombitasvir / paritaprevir / ritonavir)

Ritonavir should be taken with food to lessen gastrointestinal side effects. It is important that you take this medication exactly as prescribed by your doctor. Do not change your treatment or stop treatment without first talking to your doctor.

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Moderate

paritaprevir food

Applies to: Viekira Pak (dasabuvir / ombitasvir / paritaprevir / ritonavir), Viekira XR (dasabuvir / ombitasvir / paritaprevir / ritonavir)

Food significantly increases the absorption of paritaprevir. You should take each dose of paritaprevir with a meal. Taking it on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication.

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Therapeutic duplication warnings

Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.

Duplication

Antiviral boosters

Therapeutic duplication

The recommended maximum number of medicines in the 'antiviral boosters' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'antiviral boosters' category:

  • ritonavir (active ingredient in Viekira Pak (dasabuvir/ombitasvir/paritaprevir/ritonavir))
  • ritonavir (active ingredient in Viekira XR (dasabuvir/ombitasvir/paritaprevir/ritonavir))

Note: The benefits of taking this combination of medicines may outweigh any risks associated with therapeutic duplication. This information does not take the place of talking to your doctor. Always check with your healthcare provider to determine if any adjustments to your medications are needed.

Duplication

NS5A inhibitors

Therapeutic duplication

The recommended maximum number of medicines in the 'NS5A inhibitors' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'NS5A inhibitors' category:

  • ombitasvir (active ingredient in Viekira Pak (dasabuvir/ombitasvir/paritaprevir/ritonavir))
  • ombitasvir (active ingredient in Viekira XR (dasabuvir/ombitasvir/paritaprevir/ritonavir))

Note: The benefits of taking this combination of medicines may outweigh any risks associated with therapeutic duplication. This information does not take the place of talking to your doctor. Always check with your healthcare provider to determine if any adjustments to your medications are needed.

Duplication

Protease inhibitors

Therapeutic duplication

The recommended maximum number of medicines in the 'protease inhibitors' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'protease inhibitors' category:

  • paritaprevir (active ingredient in Viekira Pak (dasabuvir/ombitasvir/paritaprevir/ritonavir))
  • paritaprevir (active ingredient in Viekira XR (dasabuvir/ombitasvir/paritaprevir/ritonavir))

Note: The benefits of taking this combination of medicines may outweigh any risks associated with therapeutic duplication. This information does not take the place of talking to your doctor. Always check with your healthcare provider to determine if any adjustments to your medications are needed.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Disclaimer: Every effort has been made to ensure that the information provided by Multum is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. Multum's information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill, knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2018 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.

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