Drug interactions between Synthroid and warfarin
Interactions between your selected drugs
warfarin ↔ levothyroxine
Applies to:warfarin and Synthroid (levothyroxine)
If you are currently being treated with warfarin, you should let your doctor know before you start taking levothyroxine. Increasing your thyroid hormone levels can sensitize you to the effects of warfarin, which may increase your risk of bleeding. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. On the other hand, no special precautions are necessary if you have been stable on levothyroxine therapy and are now starting treatment with warfarin. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.
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