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Drug Interactions between solriamfetol and Urolene Blue

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

methylene blue solriamfetol

Applies to: Urolene Blue (methylene blue) and solriamfetol

CONTRAINDICATED: Coadministration of solriamfetol with other drugs that also inhibit the reuptake of dopamine or norepinephrine, including monoamine oxidase inhibitors (MAOIs), may increase the risk of hypertensive reactions including death, stroke, myocardial infarction, aortic dissection, pulmonary edema, and renal failure. Additionally, MAOIs can increase dopaminergic and noradrenergic activity by inhibiting the metabolism of dopamine and norepinephrine.

MANAGEMENT: Concomitant use of solriamfetol with MAOIs is considered contraindicated. At least 14 days should elapse between discontinuation of MAOI therapy and initiation of treatment with solriamfetol.

References (1)
  1. (2019) "Product Information. Sunosi (solriamfetol)." Jazz Pharmaceuticals

Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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