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Drug Interactions between sodium iodide-i-131 and Zevalin

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

No interactions were found between sodium iodide-i-131 and Zevalin. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

sodium iodide-i-131

A total of 166 drugs are known to interact with sodium iodide-i-131.

Zevalin

A total of 372 drugs are known to interact with Zevalin.

Drug and food interactions

Moderate

sodium iodide I-131 food

Applies to: sodium iodide-i-131

MONITOR: Excessive intake of dietary iodine (e.g., iodised salt) may interfere with adequate uptake of radioiodide by the thyroid .

MANAGEMENT: A diet low in iodine is recommended before initiating therapy with sodium iodide I-131 or I-123.

References (1)
  1. Cerner Multum, Inc. "Australian Product Information."
Moderate

sodium iodide I-131 food

Applies to: sodium iodide-i-131

ADJUST DOSING INTERVAL: Certain drugs may affect the pharmacokinetics, pharmacodynamics, and/or diagnostic results of radioiodides.

MANAGEMENT: Antithyroid agents such as carbimazole or propylthiouracil should generally be withheld for 1 week before administration of sodium iodide I-131 or I-123, and for a few days afterward. Salicylates, steroids, anticoagulants, antihistamines, antiparasitics, penicillins, sulfonamides, tolbutamide, thiopental, and nitroprusside should generally be withheld for 1 week. Amiodarone, lithium, and benzodiazepines should be withheld for at least 4 weeks.

References (1)
  1. (2022) "Product Information. Sodium Iodide I-123 (sodium iodide I-123)." GE Healthcare

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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