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Drug Interactions between silodosin and Tarka

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

verapamil silodosin

Applies to: Tarka (trandolapril / verapamil) and silodosin

Using silodosin together with verapamil is not recommended. Combining these medications may significantly increase the blood levels and effects of silodosin. This may cause blood pressure to fall excessively and heart rate to increase, especially when you rise from a sitting or lying position. The risk of other side effects such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity) may also increase. Let your doctor know if you develop these symptoms while using silodosin and they do not go away on their own or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medication affects you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate

trandolapril silodosin

Applies to: Tarka (trandolapril / verapamil) and silodosin

Using silodosin and trandolapril together can have increased effects on your blood pressure. You may be more likely to experience side effects such as dizziness, weakness, headache, flushing, fainting, and irregular heartbeat, especially if you have been on trandolapril and are starting treatment with silodosin. These effects may also occur following a dose increase of silodosin or when silodosin is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. You may need a dose adjustment or more frequent monitoring of your blood pressure to safely use both medications. Taking the silodosin dose just before going to bed may help. Avoid driving or operating hazardous machinery until you know how these medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Minor

verapamil trandolapril

Applies to: Tarka (trandolapril / verapamil) and Tarka (trandolapril / verapamil)

Information for this minor interaction is available on the professional version.

Drug and food interactions

Moderate

verapamil food

Applies to: Tarka (trandolapril / verapamil)

You may take verapamil with or without food, but take it the same way every time. You should avoid consuming grapefruit or grapefruit juice as much as possible during treatment with verapamil. If you have been regularly consuming grapefruit or grapefruit juice with verapamil, do not increase or decrease the amounts of these products in your diet without first talking to your doctor. Grapefruit juice can increase the blood levels and effects of verapamil. Contact your doctor if you experience sudden, unexplained weight gain; swelling of the hands, ankles, or feet; chest pain; or difficulty breathing. Avoid driving or operating hazardous machinery until you know how the medication affects you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate

trandolapril food

Applies to: Tarka (trandolapril / verapamil)

It is recommended that if you are taking trandolapril you should be advised to avoid moderately high or high potassium dietary intake. This can cause high levels of potassium in your blood. Do not use salt substitutes or potassium supplements while taking trandolapril, unless your doctor has told you to.

Moderate

silodosin food

Applies to: silodosin

Taking silodosin with food can reduce the risk and/or severity of side effects. Therefore, silodosin should be administered with or immediately after a meal.

Moderate

verapamil food

Applies to: Tarka (trandolapril / verapamil)

Ask your doctor before using verapamil together with ethanol (alcohol). Verapamil may increase the blood levels and intoxicating effects of ethanol (alcohol). This can cause symptoms of extreme drowsiness, confusion, and nausea. If you experience any of these side effect you should avoid activities requiring mental alertness. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate

verapamil food

Applies to: Tarka (trandolapril / verapamil)

Using verapamil together with multivitamin with minerals can decrease the effects of verapamil. Talk with your doctor before using verapamil and multivitamin with minerals together. You may need a dose adjustment or need your blood pressure checked more often if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.