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Drug Interactions between semaglutide and sofosbuvir / velpatasvir / voxilaprevir

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

sofosbuvir semaglutide

Applies to: sofosbuvir / velpatasvir / voxilaprevir and semaglutide

With improvement of your hepatitis C infection (HCV) during treatment with sofosbuvir, your dosage requirement of semaglutide or any other diabetic medications you are receiving may change. You may need more frequent monitoring of your blood sugar and adjustment of your diabetic regimen both during and after treatment with sofosbuvir. Let your doctor know if you experience hypoglycemia, or low blood sugar. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

velpatasvir voxilaprevir

Applies to: sofosbuvir / velpatasvir / voxilaprevir and sofosbuvir / velpatasvir / voxilaprevir

Velpatasvir may increase the blood levels of voxilaprevir in some patients. The safety of high levels of voxilaprevir has not been established. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

velpatasvir semaglutide

Applies to: sofosbuvir / velpatasvir / voxilaprevir and semaglutide

With improvement of your hepatitis C infection (HCV) during treatment with velpatasvir, your dosage requirement of semaglutide or any other diabetic medications you are receiving may change. You may need more frequent monitoring of your blood sugar and adjustment of your diabetic regimen both during and after treatment with velpatasvir. Let your doctor know if you experience hypoglycemia, or low blood sugar. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

voxilaprevir semaglutide

Applies to: sofosbuvir / velpatasvir / voxilaprevir and semaglutide

With improvement of your hepatitis C infection (HCV) during treatment with voxilaprevir, your dosage requirement of semaglutide or any other diabetic medications you are receiving may change. You may need more frequent monitoring of your blood sugar and adjustment of your diabetic regimen both during and after treatment with voxilaprevir. Let your doctor know if you experience hypoglycemia, or low blood sugar. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

voxilaprevir food

Applies to: sofosbuvir / velpatasvir / voxilaprevir

Food may help the absorption of voxilaprevir. You should take this medication with food as directed.

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Moderate

semaglutide food

Applies to: semaglutide

Food may affect the absorption of semaglutide when taken orally. It is recommended that oral semaglutide be taken 30 minutes before first food, beverage, or other oral medications of the day with no more than 4 ounces of plain water. You may experience more side effects including nausea, vomiting, and diarrhea if you fast longer than 30 minutes after the semaglutide dose. Talk to a healthcare provider if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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