Drug interactions between Promethazine with Dextromethorphan and tamoxifen
|Promethazine with Dextromethorphan (dextromethorphan/promethazine)|
Interactions between your selected drugs
tamoxifen ↔ promethazine
Applies to:tamoxifen and Promethazine with Dextromethorphan (dextromethorphan/promethazine)
Using tamoxifen together with promethazine can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect. You may be more susceptible if you have a heart condition called congenital long QT syndrome, other cardiac diseases, conduction abnormalities, or electrolyte disturbances (for example, magnesium or potassium loss due to severe or prolonged diarrhea or vomiting). Talk to your doctor if you have any questions or concerns. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with these medications, whether together or alone. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Do not stop taking any medications without consulting your healthcare provider.