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Drug Interactions between ponesimod and Precedex

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

dexmedeTOMIDine ponesimod

Applies to: Precedex (dexmedetomidine) and ponesimod

Before starting ponesimod, let your doctor know if you are currently receiving treatment with dexmedeTOMIDine. Using ponesimod in this situation can cause excessive slowing of your heart rate that can lead to serious or life-threatening cardiac complications. This is most likely to occur early on after you start treatment with ponesimod, especially within the first several hours after the first dose. On the other hand, it may be alright for you to use these medications together if you have been stable on ponesimod therapy for a while when you begin treatment with dexmedeTOMIDine. Talk to your doctor if you are uncertain whether you should be treated with these medications at the same time. Contact your doctor if you develop dizziness, lightheadedness, fainting, shortness of breath, chest pain, or heart palpitations during treatment. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Drug and food interactions

Moderate

dexmedeTOMIDine food

Applies to: Precedex (dexmedetomidine)

Alcohol can increase the nervous system side effects of dexmedeTOMIDine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with dexmedeTOMIDine. Do not use more than the recommended dose of dexmedeTOMIDine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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