Can you take Patanase with Singulair?
No drug interactions found, but 8 warnings to review for the following 2 drugs:
- Patanase (olopatadine nasal)
- Singulair (montelukast)
Drug interactions
There were no interactions found between Patanase and Singulair. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Food/lifestyle interactions
Moderate food/lifestyle interactions
Moderate:
olopatadine nasal Food/Lifestyle
Applies to: Patanase (olopatadine nasal)
Alcohol can increase the nervous system side effects of olopatadine nasal such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with olopatadine nasal. Do not use more than the recommended dose of olopatadine nasal, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
Disease interactions
7 potential interactions Applies to: 7 conditions, including Depression, Psychosis, Liver Disease, Alcoholism, and Neurotic Depression.
Alcoholism
Moderate:
Patanase
The olopatadine nasal in Patanase has a moderate potential interaction with Alcoholism.
Concurrent use of olopatadine nasal spray with alcohol or other central nervous system depressants should be avoided as additional reductions in alertness and additional impairment of the central nervous system performance may occur.
Depression
Major:
Singulair
The montelukast in Singulair has a major potential interaction with Depression.
The use of montelukast is associated with neuropsychiatric events. Patients and prescribers should be alert for neuropsychiatric events. Care should be taken before using this agent in patients with any history of mental illness. If neuropsychiatric events occur during treatment, it is recommended to carefully evaluate the risks and benefits of continuing treatment with montelukast.
Liver Disease
Moderate:
Singulair
The montelukast in Singulair has a moderate potential interaction with Liver Disease.
Reports of cholestatic hepatitis, hepatocellular liver-injury, and mixed-pattern liver injury have been reported in patients treated with montelukast sodium that had underlying potential for liver disease, such as alcohol use or other forms of hepatitis. Patients with mild-to-moderate hepatic insufficiency and clinical evidence of cirrhosis had evidence of decreased metabolism of montelukast. No dosage adjustment is required in patients with mild-to-moderate hepatic insufficiency. The pharmacokinetics of montelukast sodium in patients with more severe hepatic impairment or with hepatitis have not been evaluated. Use caution when prescribing montelukast to these patients.
Neurotic Depression
Major:
Singulair
The montelukast in Singulair has a major potential interaction with Neurotic Depression.
The use of montelukast is associated with neuropsychiatric events. Patients and prescribers should be alert for neuropsychiatric events. Care should be taken before using this agent in patients with any history of mental illness. If neuropsychiatric events occur during treatment, it is recommended to carefully evaluate the risks and benefits of continuing treatment with montelukast.
Phenylketonuria
Moderate:
Singulair
The montelukast in Singulair has a moderate potential interaction with Phenylketonuria.
Singulair (brand of montelukast) chewable tablets contain 0.842 mg of phenylalanine per each 5 mg tablet. The phenylalanine content should be considered when this product is used in patients who must restrict their intake of phenylalanine (i.e. phenylketonurics).
Psychosis
Major:
Singulair
The montelukast in Singulair has a major potential interaction with Psychosis.
The use of montelukast is associated with neuropsychiatric events. Patients and prescribers should be alert for neuropsychiatric events. Care should be taken before using this agent in patients with any history of mental illness. If neuropsychiatric events occur during treatment, it is recommended to carefully evaluate the risks and benefits of continuing treatment with montelukast.
Pulmonary Impairment
Moderate:
Singulair
The montelukast in Singulair has a moderate potential interaction with Pulmonary Impairment.
Patients with asthma on therapy with montelukast may present with systemic eosinophilia, sometimes presenting with clinical features of vasculitis consistent with Churg-Strauss syndrome, a condition which is often treated with systemic corticosteroid therapy. Prescribers should be alert to eosinophilia, vasculitic rash, worsening pulmonary symptoms, cardiac complications, and/or neuropathy presenting in their patients. Care should be taken before using this agent in patients with history of pulmonary disorders.
More resources
Patanase
A total of 287 drugs are known to interact with Patanase.
- Patanase is in the drug class nasal antihistamines and decongestants.
- Patanase is used to treat Allergic Rhinitis.
Singulair
A total of 123 drugs are known to interact with Singulair.
- Singulair is in the drug class leukotriene modifiers.
- Singulair is used to treat the following conditions:
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.