Drug Interactions between ondansetron and viloxazine
This report displays the potential drug interactions for the following 2 drugs:
- ondansetron
- viloxazine
Interactions between your drugs
ondansetron viloxazine
Applies to: ondansetron and viloxazine
MONITOR: Coadministration with viloxazine, a potent CYP450 1A2 inhibitor may increase the plasma concentrations of CYP450 1A2 substrates leading to increased toxicity. According to the prescribing information, viloxazine increased the systemic exposure (AUC) of caffeine, a probe CYP450 1A2 substrate, by nearly 6-fold without affecting its peak plasma concentration (Cmax).
MANAGEMENT: Monitor for toxicities of CYP450 1A2 substrates whenever viloxazine is added to or withdrawn from therapy. Adjust doses of CYP450 1A2 substrates as clinically indicated.
References (1)
- (2021) "Product Information. Qelbree (viloxazine)." Supernus Pharmaceuticals Inc
Drug and food interactions
No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.