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Drug Interactions between Ofev and prednisone

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

No interactions were found between Ofev and prednisone. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Ofev

A total of 173 drugs are known to interact with Ofev.

prednisone

A total of 587 drugs are known to interact with prednisone.

Drug and food interactions

Moderate

nintedanib food

Applies to: Ofev (nintedanib)

ADJUST DOSING INTERVAL: Food enhances the oral bioavailability of nintedanib. After food intake, nintedanib exposure increased by approximately 20% compared to administration under fasted conditions. Absorption was also delayed, as indicated by an increase in the median time to reach maximum plasma concentration (Tmax) from 2 hours in the fasted state to approximately 4 hours under fed conditions, irrespective of the type of food ingested.

MANAGEMENT: Nintedanib should be administered with food.

References

  1. "Product Information. Ofev (nintedanib)." Boehringer Ingelheim (2014):

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.