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Drug Interactions between Nylia 1 / 35 and telaprevir

This report displays the potential drug interactions for the following 2 drugs:

  • Nylia 1/35 (ethinyl estradiol/norethindrone)
  • telaprevir

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Interactions between your drugs

Major

ethinyl estradiol telaprevir

Applies to: Nylia 1 / 35 (ethinyl estradiol / norethindrone) and telaprevir

Telaprevir may reduce the blood levels and effects of ethinyl estradiol, which may make it less reliable as a form of birth control. You may continue to use ethinyl estradiol if desired, but two alternative, non-hormonal methods of birth control should be used during and for two weeks after treatment with telaprevir to avoid unintended pregnancy. This is particularly important because one of the other hepatitis C medications that you must use, ribavirin, is known to cause major birth defects or even death in the unborn child. Examples of non-hormonal methods of birth control include: a male condom with spermicidal jelly OR a female condom with spermicidal jelly--a combination of a male condom and a female condom is not suitable; a diaphragm with spermicidal jelly; a cervical cap with spermicidal jelly; or an intrauterine device (IUD). Talk to your gynecologist or other healthcare professional for help in selecting effective methods of birth control that work best for you. If you take hormone replacement for menopause, you should contact your doctor if you experience increased frequency or worsening of your symptoms such as hot flashes, vaginal dryness, or abnormal bleeding. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Major

norethindrone telaprevir

Applies to: Nylia 1 / 35 (ethinyl estradiol / norethindrone) and telaprevir

Telaprevir may reduce the blood levels and effects of norethindrone, which may make it less reliable as a form of birth control. You may continue to use norethindrone if desired, but two alternative, non-hormonal methods of birth control should be used during and for two weeks after treatment with telaprevir to avoid unintended pregnancy. This is particularly important because one of the other hepatitis C medications that you must use, ribavirin, is known to cause major birth defects or even death in the unborn child. Examples of non-hormonal methods of birth control include: a male condom with spermicidal jelly OR a female condom with spermicidal jelly--a combination of a male condom and a female condom is not suitable; a diaphragm with spermicidal jelly; a cervical cap with spermicidal jelly; or an intrauterine device (IUD). Talk to your gynecologist or other healthcare professional for help in selecting effective methods of birth control that work best for you. If you take hormone replacement for menopause, you should contact your doctor if you experience increased frequency or worsening of your symptoms such as hot flashes, vaginal dryness, or abnormal bleeding. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

norethindrone food

Applies to: Nylia 1 / 35 (ethinyl estradiol / norethindrone)

Grapefruit juice may increase the blood levels of certain medications such as norethindrone. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with norethindrone. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.

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Moderate

telaprevir food

Applies to: telaprevir

Food significantly increases the absorption of telaprevir. Within 30 minutes before you take each dose of telaprevir, you should eat a meal or snack containing approximately 20 grams of fat. Taking it on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication. Examples of some foods that could be taken with telaprevir include: bagel with cream cheese; half cup of nuts; 3 tablespoons of peanut butter; 1 cup of ice cream; 2 ounces of American or cheddar cheese; 2 ounces of potato chips; or half cup of trail mix. Talk to your healthcare provider if you have additional questions about how to take telaprevir.

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Minor

ethinyl estradiol food

Applies to: Nylia 1 / 35 (ethinyl estradiol / norethindrone)

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

For clinical details see professional interaction data.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.