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Drug interactions between Nplate and Promacta

Results for the following 2 drugs:
Nplate (romiplostim)
Promacta (eltrombopag)

Interactions between your drugs

There were no interactions found in our database between Nplate and Promacta - however, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

Nplate

A total of 1 drugs (2 brand and generic names) are known to interact with Nplate.

Promacta

A total of 199 drugs (1897 brand and generic names) are known to interact with Promacta.

Drug and food interactions

Moderate

eltrombopag food

Applies to: Promacta (eltrombopag)

Food may reduce the absorption and blood levels of eltrombopag. In addition, minerals such as aluminum, calcium, iron, magnesium, and zinc can also interfere with eltrombopag absorption into the bloodstream, which may make the medication less effective in treating your condition. You should take eltrombopag on an empty stomach one hour before or two hours after a meal. Eltrombopag should also be taken at least 2 hours before or 4 hours after products like antacids, mineral supplements, dairy products, and fortified juices. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Therapeutic duplication warnings

Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.

Duplication

Platelet-stimulating agents

Therapeutic duplication

The recommended maximum number of medicines in the 'platelet-stimulating agents' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'platelet-stimulating agents' category:

  • romiplostim
  • eltrombopag

Note: The benefits of taking this combination of medicines may outweigh any risks associated with therapeutic duplication. This information does not take the place of talking to your doctor. Always check with your healthcare provider to determine if any adjustments to your medications are needed.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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