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Drug interactions between nitroglycerin and vardenafil

Results for the following 2 drugs:
nitroglycerin
vardenafil

Interactions between your drugs

Major

nitroglycerin vardenafil

Applies to: nitroglycerin and vardenafil

Using vardenafil together with nitroglycerin is not recommended. Combining these medications may cause blood pressure to fall excessively, which can lead to cardiovascular collapse. The risk of other side effects such as dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity) may also increase. You should seek immediate medical attention if you experience chest pain or tightness during treatment with vardenafil. Do not use nitroglycerin on your own without consulting your doctor, even if it has been a few days since you have taken a dose of vardenafil. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

vardenafil food

Applies to: vardenafil

Grapefruit juice may increase the blood levels and effects of certain medications such as vardenafil. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with vardenafil. However, if you have been regularly consuming grapefruit or grapefruit juice with vardenafil, do not alter the amounts of these products in your diet without first talking to your doctor or other healthcare professional. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.

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Therapeutic duplication warnings

No therapeutic duplications were found for your selected drugs.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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