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Drug Interactions between nateglinide and sofosbuvir / velpatasvir / voxilaprevir

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

nateglinide sofosbuvir

Applies to: nateglinide and sofosbuvir / velpatasvir / voxilaprevir

With improvement of your hepatitis C infection (HCV) during treatment with sofosbuvir, your dosage requirement of nateglinide or any other diabetic medications you are receiving may change. You may need more frequent monitoring of your blood sugar and adjustment of your diabetic regimen both during and after treatment with sofosbuvir. Let your doctor know if you experience hypoglycemia, or low blood sugar. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate

nateglinide velpatasvir

Applies to: nateglinide and sofosbuvir / velpatasvir / voxilaprevir

With improvement of your hepatitis C infection (HCV) during treatment with velpatasvir, your dosage requirement of nateglinide or any other diabetic medications you are receiving may change. You may need more frequent monitoring of your blood sugar and adjustment of your diabetic regimen both during and after treatment with velpatasvir. Let your doctor know if you experience hypoglycemia, or low blood sugar. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate

nateglinide voxilaprevir

Applies to: nateglinide and sofosbuvir / velpatasvir / voxilaprevir

With improvement of your hepatitis C infection (HCV) during treatment with voxilaprevir, your dosage requirement of nateglinide or any other diabetic medications you are receiving may change. You may need more frequent monitoring of your blood sugar and adjustment of your diabetic regimen both during and after treatment with voxilaprevir. Let your doctor know if you experience hypoglycemia, or low blood sugar. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate

velpatasvir voxilaprevir

Applies to: sofosbuvir / velpatasvir / voxilaprevir and sofosbuvir / velpatasvir / voxilaprevir

Velpatasvir may increase the blood levels of voxilaprevir in some patients. The safety of high levels of voxilaprevir has not been established. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Drug and food interactions

Moderate

nateglinide food

Applies to: nateglinide

Alcohol may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar) may occur, depending on how much and how often you drink. You should avoid using alcohol if your diabetes is not well controlled or if you have high triglycerides, neuropathy (nerve damage), or pancreatitis. Moderate alcohol consumption generally does not affect blood glucose levels if your diabetes is under control. However, it may be best to limit alcohol intake to one drink daily for women and two drinks daily for men (1 drink = 5 oz wine, 12 oz beer, or 1.5 oz distilled spirits) in conjunction with your normal meal plan. Avoid drinking alcohol on an empty stomach or following exercise, as it may increase the risk of hypoglycemia. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate

voxilaprevir food

Applies to: sofosbuvir / velpatasvir / voxilaprevir

Food may help the absorption of voxilaprevir. You should take this medication with food as directed.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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