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Drug Interactions between mycophenolic acid and NegGram

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

nalidixic acid mycophenolic acid

Applies to: NegGram (nalidixic acid) and mycophenolic acid

Nalidixic acid may reduce the blood levels and effects of mycophenolic acid. You may need a dose adjustment of mycophenolic acid or more frequent monitoring to use both medications together. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. Seek immediate medical attention if you experience any signs or symptoms of organ rejection such as less urine output (kidney transplant); shortness of breathing, swelling, or less ability to exercise (heart transplant); or yellowing of the skin or eyes (liver transplant). It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

mycophenolic acid food

Applies to: mycophenolic acid

Take mycophenolic acid on an empty stomach 1 hour before or 2 hours after a meal unless otherwise directed by your doctor. Food may reduce the absorption of mycophenolic acid. This will make it easier for your body to absorb the medication. Do not crush, chew, or cut the tablets. The tablets have a special coating to protect the stomach from irritation.

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Moderate

nalidixic acid food

Applies to: NegGram (nalidixic acid)

Nalidixic acid and multivitamin with minerals should not be taken orally at the same time. Products that contain magnesium, aluminum, calcium, iron, and/or other minerals may interfere with the absorption of nalidixic acid into the bloodstream and reduce its effectiveness. If possible, it may be best to avoid taking multivitamin with minerals while your are being treated with nalidixic acid. Otherwise, you should take nalidixic acid either 2 hours before or 2 hours after the multivitamin with minerals dose. Talk to a healthcare professional if you are not sure whether a product contains something that could potentially interact with your medication or if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

nalidixic acid food

Applies to: NegGram (nalidixic acid)

Using caffeine together with nalidixic acid may increase the effects of caffeine. Contact your doctor if you experience headache, tremor, restlessness, nervousness, insomnia, and increased blood pressure or heart rate. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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