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Drug Interactions between morphine liposomal and Yohimbe

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Minor

yohimbine morphine liposomal

Applies to: Yohimbe (yohimbine) and morphine liposomal

A double-blind, placebo-controlled study of patients with postoperative dental pain found that while yohimbine itself did not affect pain, the overall analgesic effect of morphine was significantly enhanced in the presence of yohimbine. The mechanism of interaction is unknown. Additional research involving other pain states is needed.

References (1)
  1. Gear RW, Gordon NC, Heller PH, Levine JD (1995) "Enhancement of morphine analgesia by the alpha(2)-adrenergic antagonist yohimbine." Neuroscience, 66, p. 5-8

Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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