Drug interactions between metoprolol and Robitussin Cough & Cold D
|Robitussin Cough & Cold D (dextromethorphan/guaifenesin/pseudoephedrine)|
Interactions between your drugs
metoprolol ↔ pseudoephedrine
Applies to:metoprolol and Robitussin Cough & Cold D (dextromethorphan/guaifenesin/pseudoephedrine)
Consumer information for this interaction is not currently available.
MONITOR: Sympathomimetic agents, such as pseudoephedrine, may antagonize the effects of antihypertensives that interfere with sympathetic activity, such as alpha- and beta-adrenergic blocking agents. In contrast, alpha- and beta-blockers may diminish the vasoconstrictive effects of sympathomimetics. The mechanism of this interaction has not been reported, but may involve competitive inhibition at the adrenergic receptor. Severe hypertension may occur in patients receiving beta-blockers.
MANAGEMENT: Caution and close monitoring of blood pressure is recommended if pseudoephedrine is administered with these antihypertensives. Discontinuation of the sympathomimetic may be necessary if hypertension develops.
- Cerner Multum, Inc. "Australian Product Information." O 0
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Allegra-D (fexofenadine-pseudoephedrine)." Hoechst Marion-Roussel Inc, Kansas City, MO.
Drug and food interactions
Applies to: metoprolol
Food can enhance the levels of metoprolol in your body. You should take metoprolol at the same time each day, preferably with or immediately following meals. This will make it easier for your body to absorb the medication. Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking metoprolol. Metoprolol is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.
Therapeutic duplication warnings
No therapeutic duplications were found for your selected drugs.
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.