Drug interactions between methadone and Talwin
Interactions between your drugs
methadone ↔ pentazocine
Applies to:methadone and Talwin (pentazocine)
Using methadone together with other medications that cause central nervous system depression such as pentazocine can lead to serious side effects including respiratory distress, coma, and even death. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Do not drink alcohol or self-medicate with these medications without your doctor's approval, and do not exceed the doses or frequency and duration of use prescribed by your doctor. Also, you should avoid driving or operating hazardous machinery until you know how these medications affect you. Talk to your doctor or pharmacist if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
Applies to: methadone
Grapefruit juice can increase the blood levels and effects of methadone. If you regularly consume grapefruits or grapefruit juice, you should be monitored for side effects and/or changes in methadone levels. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. Orange juice is not expected to interact.
Applies to: Talwin (pentazocine)
Smoking tobacco may reduce the blood levels and effects of pentazocine. Contact your doctor if pentazocine is not adequately controlling your symptoms.
Therapeutic duplication warnings
No therapeutic duplications were found for your selected drugs.
Drug Interaction Classification
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.