Drug interactions between Metamucil and metformin / repaglinide
Interactions between your drugs
psyllium ↔ repaglinide
Applies to:Metamucil (psyllium) and metformin/repaglinide
Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
For clinical details see professional interaction data.
Drug and food interactions
Applies to: Metamucil (psyllium)
Psyllium may interact with other medications if given at the same time. This can cause your other medications to become less effective. In general, all oral medications should be administered at least 2 hours before or 2 hours after dosing of psyllium. Take psyllium with a full glass (at least 8 ounces) of cool water or another liquid. Taking psyllium without enough liquid may cause it to swell in the throat and cause choking.
Applies to: metformin / repaglinide
Grapefruit juice may increase the blood levels and effects of certain medications such as repaglinide. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with repaglinide. However, if you have been regularly consuming grapefruit or grapefruit juice with repaglinide, do not alter the amounts of these products in your diet without first talking to your doctor or other healthcare professional. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.
Therapeutic duplication warnings
No therapeutic duplications were found for your selected drugs.
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.