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Drug Interactions between Merzee and rifampin

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

rifAMPin ethinyl estradiol

Applies to: rifampin and Merzee (ethinyl estradiol / norethindrone)

RifAMPin may reduce the blood levels and effects of ethinyl estradiol. If you are using ethinyl estradiol for birth control, you may be at increased risk for pregnancy or breakthrough bleeding. You should discuss the use of alternative or additional methods of birth control with your healthcare provider. If you take ethinyl estradiol for another purpose, such as hormone replacement for menopause, notify your doctor if your medication is no longer controlling your symptoms or you experience abnormal bleeding. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Major

rifAMPin norethindrone

Applies to: rifampin and Merzee (ethinyl estradiol / norethindrone)

RifAMPin may reduce the blood levels and effects of norethindrone. If you are using norethindrone for birth control, you may be at increased risk for pregnancy or breakthrough bleeding. You should discuss the use of alternative or additional methods of birth control with your healthcare provider. If you take norethindrone for another purpose, such as hormone replacement for menopause, notify your doctor if your medication is no longer controlling your symptoms or you experience abnormal bleeding. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

rifAMPin food

Applies to: rifampin

Food can decrease the levels of rifAMPin in your body. Taking rifAMPin on an empty stomach (at least 30 minutes before or 2 hours after a meal) will make it easier for your body to absorb the medication. Avoid drinking alcohol while taking rifAMPin because alcohol use may increase the risk of damage to your liver. It is important to seek immediate medical care if you experience any severe side effects or symptoms of liver damage such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

norethindrone food

Applies to: Merzee (ethinyl estradiol / norethindrone)

Grapefruit juice may increase the blood levels of certain medications such as norethindrone. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with norethindrone. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.

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Minor

ethinyl estradiol food

Applies to: Merzee (ethinyl estradiol / norethindrone)

Information for this minor interaction is available on the professional version.

Minor

ethinyl estradiol food

Applies to: Merzee (ethinyl estradiol / norethindrone)

Information for this minor interaction is available on the professional version.

Minor

norethindrone food

Applies to: Merzee (ethinyl estradiol / norethindrone)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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