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Drug interactions between Mavyret and omeprazole

Results for the following 2 drugs:
Mavyret (glecaprevir/pibrentasvir)
omeprazole

Interactions between your drugs

Moderate

omeprazole glecaprevir

Applies to: omeprazole and Mavyret (glecaprevir / pibrentasvir)

Omeprazole may reduce the blood levels of glecaprevir in some patients, which may make the medication less effective in treating hepatitis C infection. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

glecaprevir food

Applies to: Mavyret (glecaprevir / pibrentasvir)

Food may help the absorption of glecaprevir. You should take this medication with food as directed.

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Therapeutic duplication warnings

No therapeutic duplications were found for your selected drugs.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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