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Drug Interactions between Marinol and tolterodine

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

droNABinol tolterodine

Applies to: Marinol (dronabinol) and tolterodine

Consumer information for this interaction is not currently available.

MONITOR: Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients. Sedation and impairment of attention, judgment, thinking, and psychomotor skills may increase.

MANAGEMENT: During concomitant use of these drugs, patients should be monitored for potentially excessive or prolonged CNS and respiratory depression. Cautious dosage titration may be required, particularly at treatment initiation. Ambulatory patients should be counseled to avoid hazardous activities requiring mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.

Drug and food/lifestyle interactions

Moderate

droNABinol food/lifestyle

Applies to: Marinol (dronabinol)

Do not use alcohol while you are receiving treatment with droNABinol. This may increase nervous system side effects such as somnolence, dizziness, confusion, difficulty concentrating, and impairment in thinking and judgment. You should also avoid consuming grapefruit and grapefruit juice, as this may increase the blood levels and effects of droNABinol. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. Take droNABinol exactly as your doctor tells you to. Do not exceed the dose of droNABinol prescribed for you or use the medication more frequently or for a longer duration than prescribed by your doctor. Also, avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medication without first talking to your doctor.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer