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Drug interactions between Malarone and Vivotif Berna Vaccine

Results for the following 2 drugs:
Malarone (atovaquone/proguanil)
Vivotif Berna Vaccine (typhoid vaccine, live)

Interactions between your drugs

Moderate

atovaquone ↔ typhoid vaccine, live

Applies to:Malarone (atovaquone/proguanil) and Vivotif Berna Vaccine (typhoid vaccine, live)

If you are currently being treated with atovaquone or have been treated within the last 3 days, you should talk to your doctor before receiving typhoid vaccine, live. Antibiotics like atovaquone can reduce the activity of the vaccine. To ensure adequate vaccine response, you should not receive typhoid vaccine, live until at least 3 days after you complete your atovaquone therapy. If you have just been vaccinated, it would be best to wait at least 3 days before using atovaquone. Your doctor may be able to prescribe a different antibiotic if you need treatment for an infection. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

typhoid vaccine, live ↔ proguanil

Applies to:Vivotif Berna Vaccine (typhoid vaccine, live) and Malarone (atovaquone/proguanil)

Ask your doctor before using typhoid vaccine, live together with proguanil. Proguanil can decrease the effectiveness of typhoid vaccine, live. Medications containing proguanil should not be administered until at least 10 days after the last dose of typhoid vaccine, live. This vaccine works by exposing you to a small dose of the virus or a protein from the virus, which causes the body to develop immunity to the disease. This vaccine will not treat an active infection that has already developed in the body. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without talking to your doctor first.

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Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Disclaimer: Every effort has been made to ensure that the information provided by Multum is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. Multum's information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill, knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2017 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.

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