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Drug Interactions between Livtencity and rosuvastatin

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

rosuvastatin maribavir

Applies to: rosuvastatin and Livtencity (maribavir)

MONITOR: Coadministration with maribavir may increase the plasma concentrations of rosuvastatin, possibly leading to signs and symptoms of myopathy and rhabdomyolysis. The proposed mechanism is decreased rosuvastatin clearance due to maribavir-mediated inhibition of the breast cancer resistance protein (BCRP) transporter. Clinical data for other BCRP substrates are lacking.

MANAGEMENT: Caution is advised when maribavir is used concurrently with rosuvastatin. Patients should be closely monitored for rosuvastatin-related adverse reactions, particularly myopathy and rhabdomyolysis. Advise patients to promptly report unexplained muscle pain, tenderness, or weakness, especially if accompanied by malaise or fever.

References (1)
  1. (2021) "Product Information. Livtencity (maribavir)." Takeda Pharmaceuticals America

Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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