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Drug Interactions between landiolol and methyldopa

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

methyldopa landiolol

Applies to: methyldopa and landiolol

Consumer information for this interaction is not currently available.

MONITOR: Centrally acting antihypertensive agents and beta-blockers may have synergistic pharmacodynamic effects resulting in marked AV block, bradycardia, hypotension, and worsening of heart failure. In addition, potentiation of the hypertensive rebound associated with abrupt withdrawal of methyldopa and the beta blocker may occur.

MANAGEMENT: Caution and monitoring of the patient's hemodynamic status are recommended during coadministration or withdrawal of these drugs.

Drug and food interactions

Moderate

methyldopa food

Applies to: methyldopa

Methyldopa and ethanol (alcohol) may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate

methyldopa food

Applies to: methyldopa

Methyldopa and multivitamin with minerals should not be taken orally at the same time. Products that contain iron may interfere with the absorption of methyldopa and reduce its effectiveness. You should separate the dosing of these medications by as much as possible. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.