Drug Interactions between Kalydeco and Seromycin Pulvules

Using cycloSERINE together with alcohol may increase the risk and/or severity of central nervous system side effects such as dizziness, drowsiness, depression, anxiety, psychoses, memory impairment, confusion, and convulsions. You should not use alcohol during treatment with cycloSERINE. In addition, using cycloSERINE together with caffeine may increase side effects such as insomnia, excitability, irritability, anxiety, tremor, psychoses, and convulsions. Do not use caffeine-containing medications without first talking to your doctor or pharmacist. You should also avoid the consumption of certain beverages or stimulants with very high caffeine levels (for example, energy drinks) during treatment with cycloSERINE. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Ivacaftor should be taken with fat-containing foods such as eggs, avocados, nuts, meat, butter, peanut butter, cheese pizza, and whole-milk dairy products to help with its absorption. Do not consume grapefruit juice or any food that contains grapefruit or Seville oranges during treatment with ivacaftor unless directed otherwise by your doctor. Grapefruit juice can significantly increase the blood levels of ivacaftor. This may increase the risk and/or severity of serious side effects such as liver damage. Call your doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes, as these may be signs and symptoms of liver damage. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.