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Drug Interactions between Jynarque and Tegsedi

This report displays the potential drug interactions for the following 2 drugs:

  • Jynarque (tolvaptan)
  • Tegsedi (inotersen)

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Interactions between your drugs

No interactions were found between Jynarque and Tegsedi. This does not necessarily mean no interactions exist. Always consult your healthcare provider.


A total of 218 drugs are known to interact with Jynarque.


A total of 226 drugs are known to interact with Tegsedi.

Drug and food interactions


tolvaptan food

Applies to: Jynarque (tolvaptan)

You should avoid drinking grapefruit juice during treatment with tolvaptan. Grapefruit juice can cause too much of the medication to be in the blood. Serious nervous system side effects such as difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, and coma may occur. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.