Can you take Japanese encephalitis virus vaccine nakayama with Myhibbin?
1 drug interaction and 11 additional warnings found for the following 2 drugs:
- japanese encephalitis virus vaccine nakayama
- Myhibbin (mycophenolate mofetil)
Drug interactions
Moderate drug interactions
Moderate:
Japanese encephalitis virus vaccine Nakayama mycophenolate mofetil
Applies to: japanese encephalitis virus vaccine nakayama and Myhibbin (mycophenolate mofetil)
If you are currently being treated or have recently been treated with mycophenolate mofetil, you should let your doctor know before receiving Japanese encephalitis virus vaccine Nakayama. Depending on the dose and length of time you have been on mycophenolate mofetil, you may have a reduced response to the vaccine. In some situations, your doctor may want to delay vaccination to give your body time to recover from the effects of mycophenolate mofetil therapy. If you have recently been vaccinated with Japanese encephalitis virus vaccine Nakayama, your doctor may choose to postpone treatment with mycophenolate mofetil for a couple of weeks or more. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Food/lifestyle interactions
No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Disease interactions
11 potential interactions Applies to: 11 conditions, including Fever, Inflammatory Bowel Disease, Peptic Ulcer, Liver Disease, and Infection.
Fever
Major:
japanese encephalitis virus vaccine nakayama
Japanese encephalitis virus vaccine Nakayama has a major potential interaction with Fever.
Ideally, vaccination should occur when an individual is healthy, thus minimizing the risk of an adverse host reaction and/or vaccine failure. However, a current or recent infection does not necessarily preclude the use of vaccines, depending on the severity of the patient's symptoms and their etiology. Superficial infections and minor acute illnesses such as a mild upper respiratory infection with or without low-grade fever do not contraindicate immunization, particularly if prompt administration of a vaccine is deemed necessary or beneficial. In fact, when vaccines are administered during the course of a minor illness, the risk of adverse events is not increased, and serum antibody response is not often diminished. On the other hand, if fever or symptoms suggest a moderate or severe illness, it is usually appropriate to withhold vaccination until the patient has recovered. In addition to the potential risks already mentioned, evolving signs and symptoms of the illness can sometimes confound the diagnosis of a vaccine reaction if it develops. In the presence of any infection, the decision to administer or withhold/defer immunization should take into consideration the benefits versus the risks to an individual patient.
Gastrointestinal Hemorrhage
Moderate:
Myhibbin
The mycophenolate mofetil in Myhibbin has a moderate potential interaction with Gastrointestinal Hemorrhage.
Gastrointestinal, rectal, and duodenal hemorrhage, hemorrhagic pancreatitis and rarely, large-intestine perforation have occurred in patients receiving mycophenolate. These events occurred primarily at dosages of mycophenolate >2 grams per day. Therapy with mycophenolate should be administered cautiously in patients with active gastrointestinal disease.
Immunodeficiency
Moderate:
japanese encephalitis virus vaccine nakayama
Japanese encephalitis virus vaccine Nakayama has a moderate potential interaction with Immunodeficiency.
The expected serum antibody responses may not be obtained when vaccines and/or toxoids are administered to patients with primary or acquired immunodeficiency, including those with severe combined immunodeficiency, hypogammaglobulinemia or agammaglobulinemia, HIV infection, altered immune states (due to diseases such as leukemia, lymphoma, or generalized malignancy), or immunosuppression due to drug or other treatments (e.g., corticosteroids, alkylating agents, antimetabolites, or radiation).
Infection
Major:
japanese encephalitis virus vaccine nakayama
Japanese encephalitis virus vaccine Nakayama has a major potential interaction with Infection.
Ideally, vaccination should occur when an individual is healthy, thus minimizing the risk of an adverse host reaction and/or vaccine failure. However, a current or recent infection does not necessarily preclude the use of vaccines, depending on the severity of the patient's symptoms and their etiology. Superficial infections and minor acute illnesses such as a mild upper respiratory infection with or without low-grade fever do not contraindicate immunization, particularly if prompt administration of a vaccine is deemed necessary or beneficial. In fact, when vaccines are administered during the course of a minor illness, the risk of adverse events is not increased, and serum antibody response is not often diminished. On the other hand, if fever or symptoms suggest a moderate or severe illness, it is usually appropriate to withhold vaccination until the patient has recovered. In addition to the potential risks already mentioned, evolving signs and symptoms of the illness can sometimes confound the diagnosis of a vaccine reaction if it develops. In the presence of any infection, the decision to administer or withhold/defer immunization should take into consideration the benefits versus the risks to an individual patient.
Inflammatory Bowel Disease
Moderate:
Myhibbin
The mycophenolate mofetil in Myhibbin has a moderate potential interaction with Inflammatory Bowel Disease.
Gastrointestinal, rectal, and duodenal hemorrhage, hemorrhagic pancreatitis and rarely, large-intestine perforation have occurred in patients receiving mycophenolate. These events occurred primarily at dosages of mycophenolate >2 grams per day. Therapy with mycophenolate should be administered cautiously in patients with active gastrointestinal disease.
Lesch-Nyhan Syndrome
Moderate:
Myhibbin
The mycophenolate mofetil in Myhibbin has a moderate potential interaction with Lesch-Nyhan Syndrome.
Mycophenolate mofetil is an inosine monophosphate dehydrogenase (IMPDH) inhibitor; therefore it should be avoided in patients with hereditary deficiencies of hypoxanthine-guanine phosphoribosyl-transferase (HGPRT) such as Lesch-Nyhan and Kelley-Seegmiller syndromes because it may cause an exacerbation of disease symptoms characterized by the overproduction and accumulation of uric acid leading to symptoms associated with gout such as acute arthritis, tophi, nephrolithiasis or urolithiasis and renal disease including renal failure.
Liver Disease
Moderate:
Myhibbin
The mycophenolate mofetil in Myhibbin has a moderate potential interaction with Liver Disease.
Mycophenolate mofetil (inactive) undergoes complete presystemic metabolism to active MPA , further metabolism to inactive forms, some of which undergo enterohepatic circulation producing a second peak of MPA. Alcoholic cirrhosis (parenchymal cell damage) does not appear to affect the metabolism of MPA to inactive forms. Hepatic disease/dysfunction due to other etiologies may induce different effects.
Neutropenia
Major:
Myhibbin
The mycophenolate mofetil in Myhibbin has a major potential interaction with Neutropenia.
Severe neutropenia has occurred in up to 2% of patients administered mycophenolate. Therapy with mycophenolate should be administered cautiously in patients with or predisposed to neutropenia. Mycophenolate should be discontinued or the dose reduced in patients who develop neutropenia (absolute neutrophil count <1300/mm3). Clinical monitoring of hematopoietic function is recommended. Complete blood counts should be performed weekly during the first month, two times a month during the second and third months, and monthly for the remainder of the first year of treatment.
Peptic Ulcer
Moderate:
Myhibbin
The mycophenolate mofetil in Myhibbin has a moderate potential interaction with Peptic Ulcer.
Gastrointestinal, rectal, and duodenal hemorrhage, hemorrhagic pancreatitis and rarely, large-intestine perforation have occurred in patients receiving mycophenolate. These events occurred primarily at dosages of mycophenolate >2 grams per day. Therapy with mycophenolate should be administered cautiously in patients with active gastrointestinal disease.
Renal Dysfunction
Moderate:
Myhibbin
The mycophenolate mofetil in Myhibbin has a moderate potential interaction with Renal Dysfunction.
Mycophenolate undergoes complete presystemic metabolism to its active form, MPA . Less than 1% of MPA is excreted in the urine. In a single-dose study, the area under the curve (AUC) for MPA in patients with severe chronic renal impairment (creatinine clearance <25 mL/min) was approximately 75% greater than those of healthy volunteers (creatinine clearance >80 mL/min). The AUC for the inactive metabolite was 3 to 6 times higher. Multiple dose studies have not been performed. No data are available for cardiac transplant patients with severe renal impairment and when benefit outweighs risk, therapy with mycophenolate should be administered with extreme caution.
Vaccination
Moderate:
Myhibbin
The mycophenolate mofetil in Myhibbin has a moderate potential interaction with Vaccination.
During treatment with mycophenolate mofetil, the use of live attenuated vaccines should be avoided and patients should be advised that vaccinations may be less effective. Advise patients to discuss with the physician before seeking any immunizations.
More resources
japanese encephalitis virus vaccine nakayama
A total of 339 drugs are known to interact with japanese encephalitis virus vaccine nakayama.
- Japanese encephalitis virus vaccine nakayama is in the drug class viral vaccines.
- Japanese encephalitis virus vaccine nakayama is used to treat Japanese Encephalitis Virus Prophylaxis.
Myhibbin
A total of 365 drugs are known to interact with Myhibbin.
- Myhibbin is in the drug class selective immunosuppressants.
- Myhibbin is used to treat Organ Transplant, Rejection Prophylaxis.
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.