Drug Interactions between Ixempra and Laniroif
This report displays the potential drug interactions for the following 2 drugs:
- Ixempra (ixabepilone)
- Laniroif (aspirin/butalbital/caffeine)
Interactions between your drugs
butalbital ixabepilone
Applies to: Laniroif (aspirin / butalbital / caffeine) and Ixempra (ixabepilone)
Consumer information for this interaction is not currently available.
MONITOR: Coadministration with inducers of CYP450 3A4 may decrease the plasma concentrations of ixabepilone, which is primarily metabolized by the isoenzyme. According to the manufacturer, coadministration of ixabepilone with the potent CYP450 3A4 inducer rifampin decreased ixabepilone systemic exposure (AUC) by 43% compared to administration of ixabepilone alone. Reduced efficacy of ixabepilone may occur. However, the extent to which less potent CYP450 3A4 inducers interact with ixabepilone is unknown.
MANAGEMENT: The potential for diminished pharmacologic effects of ixabepilone should be considered during coadministration with CYP450 3A4 inducers. Caution is advised if they are used with ixabepilone, and alternative treatments may be required if an interaction is suspected.
References
- "Product Information. Ixempra (ixabepilone)." R-Pharm US LLC (2023):
aspirin caffeine
Applies to: Laniroif (aspirin / butalbital / caffeine) and Laniroif (aspirin / butalbital / caffeine)
Information for this minor interaction is available on the professional version.
Drug and food interactions
butalbital food
Applies to: Laniroif (aspirin / butalbital / caffeine)
Ask your doctor before using butalbital together with ethanol, this can add to dizziness, drowsiness and other side effects of butalbital. Be careful if you drive or do activities that require you to be awake and alert. Talk with your doctor before using any medications together, or drinking alcohol with butalbital. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
ixabepilone food
Applies to: Ixempra (ixabepilone)
Do not consume grapefruit or grapefruit juice during treatment with ixabepilone unless specifically directed otherwise by your doctor. Ixabepilone can interact with grapefruit and grapefruit juice and the interaction may increase the effects of ixabepilone. You should discuss the use of grapefruit and grapefruit juice with your doctor.
aspirin food
Applies to: Laniroif (aspirin / butalbital / caffeine)
Ask your doctor before using aspirin together with ethanol. Do not drink alcohol while taking aspirin. Alcohol can increase your risk of stomach bleeding caused by aspirin. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
caffeine food
Applies to: Laniroif (aspirin / butalbital / caffeine)
Information for this minor interaction is available on the professional version.
aspirin food
Applies to: Laniroif (aspirin / butalbital / caffeine)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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