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Drug Interactions between Ixempra and Kepivance

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

palifermin ixabepilone

Applies to: Kepivance (palifermin) and Ixempra (ixabepilone)

Palifermin is used to treat painful mouth ulcers that can occur from chemotherapy. However, the timing of the dosing of palifermin relative to chemotherapy is important. Palifermin should generally not be used within 24 hours before or after chemotherapy. Otherwise, the mouth ulcers may actually worsen or heal more slowly. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

ixabepilone food

Applies to: Ixempra (ixabepilone)

Do not consume grapefruit or grapefruit juice during treatment with ixabepilone unless specifically directed otherwise by your doctor. Ixabepilone can interact with grapefruit and grapefruit juice and the interaction may increase the effects of ixabepilone. You should discuss the use of grapefruit and grapefruit juice with your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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