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Drug interactions between itraconazole and omeprazole

Results for the following 2 drugs:
itraconazole
omeprazole

Interactions between your drugs

Moderate

itraconazole omeprazole

Applies to: itraconazole and omeprazole

Talk to your doctor before using itraconazole together with omeprazole. Combining these medications may interfere with the absorption of itraconazole and reduce its effectiveness. Your doctor may be able to prescribe alternative medications that do not interact, or you may need a dose adjustment to safely use both medications. Taking itraconazole with a cola beverage may also help by increasing stomach acid. Contact your doctor if your infection does not improve or gets worse. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

itraconazole food

Applies to: itraconazole

Food increases the absorption of itraconazole capsules but decreases the absorption of itraconazole oral solution. Capsules should be taken immediately after a full meal and the solution be taken on an empty stomach to ensure best results.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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