Drug interactions between hydrochlorothiazide and Methotrexate LPF Sodium
|Methotrexate LPF Sodium (methotrexate)|
Interactions between your drugs
Applies to: Methotrexate LPF Sodium (methotrexate) and hydrochlorothiazide
Before taking methotrexate, tell your doctor if you also use hydroCHLOROthiazide. You may need dose adjustments or special tests in order to safely take both medications together. Your blood work may need to be monitored more frequently or using a different blood pressure medicine may be necessary. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using your medications without first talking to your doctor first.
Drug and food interactions
Applies to: Methotrexate LPF Sodium (methotrexate)
Caffeine may reduce the effectiveness of methotrexate in the treatment of arthritis. If you are receiving methotrexate for arthritis, you may want to limit your intake of caffeine-containing foods and medications. Check with your doctor or pharmacist if you have concerns or are uncertain what products may contain caffeine.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.