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Drug Interactions between house dust mite allergen extract and landiolol

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

house dust mite allergen extract landiolol

Applies to: house dust mite allergen extract and landiolol

Consumer information for this interaction is not currently available.

GENERALLY AVOID: Beta-blockers may attenuate the response to epinephrine and inhaled bronchodilators in the treatment of serious systemic reactions, including anaphylaxis, that may occur during immunotherapy with allergenic extracts. Noncardioselective beta-blockers, in particular, can antagonize the bronchodilating effects of beta-agonists by blocking beta-2 adrenergic receptors in smooth muscles of the bronchial tree, although cardioselective beta-blockers may occasionally do the same, as beta-1 selectivity is not absolute and may be lost at higher dosages in susceptible patients. All beta-blockers can antagonize the cardiostimulatory effects of beta-agonists by blocking beta-1 adrenergic receptors in the heart.

MANAGEMENT: Immunotherapy with allergenic extracts may not be appropriate in patients receiving beta-blockers, as these patients may be unresponsive to the usual doses of beta-agonists that may be required to reverse a systemic reaction. Canadian authorities consider the use of allergenic extracts to be contraindicated in patients on beta-blockers.

Drug and food interactions

Moderate

house dust mite allergen extract food

Applies to: house dust mite allergen extract

Consuming food or beverage during or immediately after using house dust mite allergen extract may reduce the amount of allergen extract available for absorption from tissues under the tongue into the blood stream. Food or beverage should not be taken with, or for at least 5 minutes after, using house dust mite allergen extract. Use of alcohol with house dust mite allergen extract may increase the risk and severity of allergic reactions that can sometimes occur during treatment with house dust mite allergen extract. Potentially life-threatening or fatal reactions may occur. Talk to your doctor if you have any questions or concerns. Stop using house dust mite allergen extract, administer epinephrine, and seek immediate medical attention if signs and symptoms of an allergic reaction develop such as trouble breathing, swallowing, or speaking; throat tightness or swelling; dizziness, lightheadedness, or fainting; rapid or weak heartbeat; severe stomach cramps or pain; vomiting or diarrhea; and/or severe flushing or itching. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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